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Antigenic Specificity | N/H/K-Ras |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: N/H/K-Ras Polyclonal Antibody detects endogenous levels of N/H/K-Ras protein. HRAS belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. GTPase Hras undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human N/H/K-Ras at AA range: 10-90 |
Other Names | [Rabbit N/H/K-Ras; NRAS; HRAS1; GTPase NRas; Transforming protein N-Ras; HRAS; HRAS1; GTPase HRas; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras; KRAS; KRAS2; RASK2; GTPase KRas; K-Ras 2; Ki-Ras; c-K-ras; c-Ki-ras] |
Gene, Accession # | [N/H/K-Ras], Gene ID: 4893, NCBI: NP_002515.1, UniProt: P01111 |
Catalog # | MBS9700697 |
Price | $250, $250 |
Order / More Info | N/H/K-Ras Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |