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Antigenic Specificity | Human IL-1beta |
Clone | [464] |
Host Species | Mouse |
Reactive Species | human. other species not tested. does not show any cross reaction with recombinant human IL-1alpha, recombinant murine IL-1alpha or IL-1beta. |
Isotype | IgM,k |
Format | Protein G purified |
Size | 0.5 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Reactive with natural and recombinant human Interleukin-1 Beta (IL-1beta). Interleukin 1 Beta (IL-1Beta) shares the IL-1 receptor with other cytokines in IL-1 family. It is primarily produced by activated macrophage as a proprotein, which is cleaved by caspase 1 to become active. Like IL-1 Alpha, IL-1Beta is an important mediator of innate immunity. IL-1Beta stimulates lymphocyte proliferation and the production of TNF-Alpha, IL-6 and IL-8. IL-1Beta and TNF-Alpha can synergically act at NGkB and mitogen kinases including JNKs and p38 MARKs, thus leading to the selective expression of genes for immunity and inflammation. |
Immunogen | Immunogen: Purified recombinant human IL-1beta. Myeloma: Sp2/0-Ag14. Light Chain: Kappa. |
Other Names | [Interleukin-1 Beta (IL-1beta); Interleukin-1 Beta (IL-1b); Mouse to human Interleukin-1 beta (IL-1beta)], [IL1B; IL1B; IL-1; IL1F2; IL1-BETA] |
Gene, Accession # | [IL-1beta], Gene ID: 3553, NCBI: NP_000567.1 |
Catalog # | MBS592009 |
Price | $490 |
Order / More Info | Human IL-1beta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |