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Antigenic Specificity | CHRNA3 (N-term), 25-52 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CHRNA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human CHRNA3. CHRNA3 locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been |
Immunogen | n/a |
Other Names | [Neuronal acetylcholine receptor subunit alpha-3; CHRNA3; NACHRA3] |
Gene, Accession # | [CHRNA3], Gene ID: 1136, NCBI: NP_000734.2, UniProt: P32297 |
Catalog # | MBS9202130 |
Price | $165, $370 |
Order / More Info | CHRNA3 (N-term), 25-52 Antibody from MYBIOSOURCE INC. |
Product Specific References | Cho, M.H., et al. Nat. Genet. 42(3):200-202(2010) Girard, N., et al. Clin. Cancer Res. 16(2):755-763(2010) Grando, S.A., et al. J. Invest. Dermatol. 105(6):774-781(1995) |