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Antigenic Specificity | Presenilin 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Presenilin-2(PSEN2) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat. Background: Presenilin-2 is a protein that in humans is encoded by the PSEN2 gene. Kovacs et al.(1996) demonstrated that the expression patterns of PS1 and PS2 in the brain are extremely similar to each other and that messages for both are primarily detectable in neuronal populations. Immunochemical analyses indicated that PS1 and PS2 are similar in size and localize to similar intracellular compartments(endoplasmic reticulum and Golgi complex). Li et al.(1997) demonstrated that wildtype PS1 and PS2 are localized to the nuclear membrane, its associated interphase kinetochores, and the centrosomes.In melanocytic c |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Presenilin 2 (39-51aa EDGENTAQWRSQE), different from the related mouse and rat sequences by two amino acids. |
Other Names | [Presenilin-2(PS-2); presenilin 2(Alzheimer disease 4); AD3L; AD3LP; AD4; AD5; Alzheimer disease 4; CMD1V; E5-1; OTTHUMP00000035671; OTTHUMP00000035672; OTTHUMP00000228286; OTTHUMP00000228288; Presenilin 2(Alzheimer disease 4); Presenilin 2; Presenilin-2 CTF subunit; PS-2; PS2; Psen2; PSN2_HUMAN; PSNL2; STM-2; STM2], [PSEN2; PSEN2; AD4; PS2; AD3L; STM2; CMD1V; AD4; PS2; PSNL2; STM2; PS-2] |
Gene, Accession # | [PSEN2], Gene ID: 5664, NCBI: P49810.1, UniProt: P49810 |
Catalog # | MBS175630 |
Price | $315 |
Order / More Info | Presenilin 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |