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Antigenic Specificity | POMK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human POMK (NP 115613.1). |
Other Names | [SGK196; MDDGA12; MDDGC12] |
Gene, Accession # | [POMK], Gene ID: 84197, NCBI: NP_001264900.1, UniProt: Q9H5K3 |
Catalog # | MBS8549954 |
Price | $280 |
Order / More Info | POMK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |