LDHA Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LDHA |
| Clone | [AT1A4] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, k |
| Format | Protein G purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1mg/ml |
| Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Lactate through lactate dehydrogenase A (LDHA), which is encoded by a target gene of c-Myc and hypoxia-inducible factor (HIF-1). LDHA expression is repressed by SugR in the absence of sugar. Reduction of LDHA causes bioenergetic and oxidative stress leading to cell death. LDHA (LDH-5, M-LDH, or A4), which is the predominant form in skeletal muscle, kinetically favors the conversion of pyruvate to lactate. Therefore, LDH-A is an attractive target for cancer therapy since its expression is largely relegated to skeletal muscle. |
| Immunogen | Immunogen: Recombinant human LDHA (1-332aa) purified from E Coli |
| Other Names | [L-lactate dehydrogenase A chain; GSD11; LDH1; LDHM; PIG19; L-lactate dehydrogenase A chain Cell proliferation-inducing gene 19 protein; LDH muscle subunit; M LDH; L lactate dehydrogenase A chain; l7R2; Lactate dehydrogenase 1; A chain; Lactate dehydrogenase A; Lactate dehydrogenase A4; Lactate dehydrogenase M; LDH muscle subunit; OTTMuSP00000017774; Proliferation-inducing gene 19; Renal carcinoma antigen NY-REN-59.], [LDHA; LDHA; LDHM; GSD11; PIG19; HEL-S-133P; LDH-A; LDH-M] |
| Gene, Accession # | [LDHA], Gene ID: 3939, NCBI: NP_005557, UniProt: P00338 |
| Catalog # | MBS200176 |
| Price | $240, $315 |
| Order / More Info | LDHA Antibody from MYBIOSOURCE INC. |
| Product Specific References | Le A, et al. (2010) Proc Natl Acad Sci U S A, 107 (5):2037-42.; Xie H, et al. (2009) Mol Cancer Ther, 8 (3):626-35.; Toyoda K, et al. (2010) J Bacteriol, 191 (13):4251-8. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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