LEF1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLEF1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration0.8 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total LEF1 protein. This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human lymphoid enhancer-binding factor 1
Other Names[LEF-1; TCF10; TCF7L3; TCF1ALPHA]
Gene, Accession #[LEF1], Gene ID: 51176, NCBI: NP_001124185.1, UniProt: Q9UJU2
Catalog #MBS9409519
Price$255
Order / More InfoLEF1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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