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Antigenic Specificity | LEF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.8 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total LEF1 protein. This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human lymphoid enhancer-binding factor 1 |
Other Names | [LEF-1; TCF10; TCF7L3; TCF1ALPHA] |
Gene, Accession # | [LEF1], Gene ID: 51176, NCBI: NP_001124185.1, UniProt: Q9UJU2 |
Catalog # | MBS9409519 |
Price | $255 |
Order / More Info | LEF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |