Kir6.2 (Phospho-Thr224) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKir6.2 (Phospho-Thr224)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous levels of Kir6.2 only when phosphorylated at threonine 224. This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium By similarity. Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 form
ImmunogenImmunogen Type: peptide Immunogen Description: Peptide sequence around phosphorylation site of threonine 224 (K-T-TP-S-P) derived from Human Kir6.2.
Other Names[ATP-sensitive inward rectifier potassium channel 11; IKATP; IRK11; Inward rectifier K channel Kir6.2; KCNJ11; Potassium channel; inwardly rectifying; subfamily J; member 11]
Gene, Accession #[Kir6.2], Gene ID: 3767, NCBI: NP_001159762.1, UniProt: Q14654
Catalog #MBS9400901
Price$200, $255
Order / More InfoKir6.2 (Phospho-Thr224) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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