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Antigenic Specificity | Mouse Interleukin-10 |
Clone | [NYRmIL-10] |
Host Species | Rat |
Reactive Species | n/a |
Isotype | IgM |
Format | purified |
Size | 0.4 mg, 1 mg |
Concentration | 1mg/ml in PBS (after reconstitution). |
Applications | ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Intracellular staining |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. |
Immunogen | Immunogen: r.Murine IL-10. |
Other Names | [IL 10; Interleukin-10, Rat Mouse; B-TCGF; CSIF; TGIF; IL-10; IL10A; MGC126450; MGC126451; Cytokine synthesis inhibitory factor; IL-10], [SPPV_03] |
Gene, Accession # | [IL-10], Gene ID: 944684, NCBI: NP_659579.1 |
Catalog # | MBS140014 |
Price | $305, $455 |
Order / More Info | Mouse Interleukin-10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |