Human ATG4D Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human ATG4D |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Peptide Affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ATG4D, Auotphagy related 4D, cysteine peptidases, belong to the autophagy-related protein 4 family of C54 endopeptidases. Members of this family play a role in the biogenesis of autophagosomes (1). Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms (2). |
| Immunogen | Immunogen: Synthetic peptide from the C-terminal of human ATG4D. Immunogen Species: Human |
| Other Names | [APG4 autophagy 4 homolog D; APG4 D; ATG4 autophagy related 4 homolog D; AUTL4; Cysteine protease ATG4D; MGC31226; ATG4D : HRP; Rabbit Human ATG4D; Rabbit Human ATG4D; ATG4D], [ATG4D; ATG4D; APG4D; AUTL4; APG4-D; APG4D; AUTL4] |
| Gene, Accession # | [ATG4D], Gene ID: 84971, NCBI: NP_001268433.1, UniProt: Q86TL0 |
| Catalog # | MBS807400 |
| Price | $425 |
| Order / More Info | Human ATG4D Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: Autophagy related 4D, cysteine peptidase. 2. Li M., et al. (2011) J Biol Chem. 286: 7327-7338. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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