Edit |   |
---|---|
Antigenic Specificity | TNFRSF10C - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against TNFRSF10C. It was validated on Western Blot using a cell lysate as a positive control.Target Description: TNFRSF10C is the receptor for the cytotoxic ligand TRAIL. TNFRSF10C lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. TNFRSF10C may protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TNFRSF10C |
Other Names | [tumor necrosis factor receptor superfamily member 10C; Tumor necrosis factor receptor superfamily member 10C; tumor necrosis factor receptor superfamily member 10C; TNF receptor superfamily member 10c; Antagonist decoy receptor for TRAIL/Apo-2L; Decoy TRAIL receptor without death domain; Decoy receptor 1; DcR1; Lymphocyte inhibitor of TRAIL; TNF-related apoptosis-inducing ligand receptor 3; TRAIL receptor 3; TRAIL-R3; TRAIL receptor without an intracellular domain; CD_antigen: CD263] |
Gene, Accession # | [TNFRSF10C], Gene ID: 8794, NCBI: NP_003832, UniProt: O14798 |
Catalog # | MBS3224350 |
Price | $335 |
Order / More Info | TNFRSF10C - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |