Edit |   |
---|---|
Antigenic Specificity | CD80 |
Clone | [2A2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: The protein CD80 (Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7.1. Its principal mode of action is by binding to CD28. Along with CD86, these molecules provide the necessary stimuli to prime T cells against antigens presented by antigen-presenting cells. CD80 and CD86 also bind to CTLA-4, a cell surface molecule expressed on activated T cells. Interactions between CD80 or CD86 with CTLA-4 decrease the response of T cells. Mouse research by scientists at Emory University showed that estrogen-related bone loss is linked to recently discovered pathways involving various proteins, suc |
Immunogen | Immunogen: Purified recombinant fragment of CD80 expressed in E Coli. |
Other Names | [CD28LG; LAB7; B7.1], [CD28LG; LAB7; B7.1] |
Gene, Accession # | [CD80], Gene ID: 397161, NCBI: AAL58443.1 |
Catalog # | MBS475913 |
Price | $335 |
Order / More Info | CD80 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |