ACSL1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityACSL1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionRabbit IgG polyclonal antibody for Long-chain-fatty-acid--CoA ligase 1(ACSL1) detection. Background: Long-chain-fatty-acid - CoA ligase 1 is an enzyme that in humans is encoded by the ACSL1 gene. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. This specific protein is most commonly found in mitochondria and peroxisomes.
ImmunogenImmunogen: E. coli-derived human ACSL1 recombinant protein (Position: D604-V698). Human ACSL1 shares 81.1% and 86.3% amino acid (aa) sequence identity with mouse and rat ACSL1, respectively.
Other Names[ACS 1; ACS1; ACSL 1; ACSL1; FACL 1; FACL1; FACL 2; FACL2; LACS 1; LACS1; LACS 2; LACS2; P33121; Long-chain-fatty-acid--CoA ligase 1; acyl-CoA synthetase long-chain family member 1], [ACSL1; ACSL1; ACS1; LACS; FACL1; FACL2; LACS1; LACS2; FACL1; FACL2; LACS; LACS1; LACS2; ACS1; LACS 1; LACS 2]
Gene, Accession #[ACSL1], Gene ID: 2180, NCBI: NP_001273637.1, UniProt: P33121
Catalog #MBS178781
Price$315
Order / More InfoACSL1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Meloni I, Muscettola M, Raynaud M, Longo I, Bruttini M, Moizard MP, Gomot M, Chelly J, des Portes V, Fryns JP, Ropers HH, Magi B, Bellan C, Volpi N, Yntema HG, Lewis SE, Schaffer JE, Renieri A (Apr 2002). FACL4, encoding fatty acid-CoA ligase 4, is mutated in nonspecific X-linked mental retardation. Nature Genetics 30 (4): 436-40.2. Longo I, Frints SG, Fryns JP, Meloni I, Pescucci C, Ariani F, Borghgraef M, Raynaud M, Marynen P, Schwartz C, Renieri A, Froyen G (Jan 2003). A third MRX family (MRX68) is the result of mutation in the long chain fatty acid-CoA ligase 4 (FACL4) gene: proposal of a rapid enzymatic assay for screening mentally retarded patients. Journal of Medical Genetics 40 (1): 11-7.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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