Human Siglec-3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Siglec-3
Clone[5C24]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionSiglecs are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal, Ig-like V-type domain that mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains (2 to 17), a single transmembrane region, and a cytoplasmic tail. The siglecs can be broadly classified into two subgroups: siglecs-1, -2, and -4, and a siglec-3/CD33-related subgroup (siglecs-3, and -5 through -13 in primates) defined by sequence similarity and clustered gene localization. They are widely expressed on hematopoietic cells, often in a cell-type-specific manner, and siglec-4/MAG is a myelin component in Schwann cells and oligodendrocytes. Their ligands, sialic acids, are negatively charged monosaccharides f
ImmunogenAntibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with the extracellular domain of recombinant human Siglec-3, also called CD33.
Other Names[CD33; p67; SIGLEC3; SIGLEC-3], [CD33; CD33; p67; SIGLEC3; SIGLEC-3; SIGLEC3; Siglec-3]
Gene, Accession #[Siglec-3], Gene ID: 945, NCBI: NP_001076087.1, UniProt: P20138
Catalog #MBS690982
Price$490
Order / More InfoHuman Siglec-3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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