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Antigenic Specificity | Acinus (CT) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-Acinus (CP) [Rabbit antibody to peptide corresponding to aa 307-322 of human Acinus S and aa 338-353 of human Acinus S'. Recognizes human and mouse Acinus.]. This antibody recognizes human and mouse Acinus (220 kD). Chromatin condensation and nuclear fragmentation (CCNF) are the hallmark of apoptosis. CCNF is triggered by the activation of members of the caspase family, caspase-activated DNase, and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for Apoptotic Chromatin Condensation Inducer in the Nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease to generate a small active peptide, p17, which causes chromatin cond |
Immunogen | Antigen: Peptide corresponding to aa 1065-1080 of human AcinusL, aa 307- 322 of human Acinus S and aa 338-353 of human AcinusS' which are identical to those of mouse Acinus. These sequences are located near the Cterminus of the cleaved active peptide p17. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS194014 |
Price | $415 |
Order / More Info | Acinus (CT) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |