Edit |   |
Antigenic Specificity | Phospho-Caspase 6 (S257) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Caspase 6 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S257 of human Caspase 6. Caspase 6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. |
Immunogen | n/a |
Other Names | [Caspase-6; CASP-6; Apoptotic protease Mch-2; Caspase-6 subunit p18; Caspase-6 subunit p11; CASP6; MCH2] |
Gene, Accession # | [CASP6], Gene ID: 839, NCBI: NP_001217.2, UniProt: P55212 |
Catalog # | MBS9212815 |
Price | $165, $370 |
Order / More Info | Phospho-Caspase 6 (S257) Antibody from MYBIOSOURCE INC. |
Product Specific References | Kalinin, A.E., et al., J. Invest. Dermatol. 124(1):46-55 (2005). Suzuki, A., et al., Oncogene 23(42):7067-7075 (2004). Horowitz, P.M., et al., J. Neurosci. 24(36):7895-7902 (2004). Schmeck, B., et al., Infect. Immun. 72(9):4940-4947 (2004). Mendez, E., et al., J. Virol. 78(16):8601-8608 (2004). |