Phospho-Caspase 6 (S257) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-Caspase 6 (S257)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: bovine, mouse, rat)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis Caspase 6 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S257 of human Caspase 6. Caspase 6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.
Immunogenn/a
Other Names[Caspase-6; CASP-6; Apoptotic protease Mch-2; Caspase-6 subunit p18; Caspase-6 subunit p11; CASP6; MCH2]
Gene, Accession #[CASP6], Gene ID: 839, NCBI: NP_001217.2, UniProt: P55212
Catalog #MBS9212815
Price$165, $370
Order / More InfoPhospho-Caspase 6 (S257) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKalinin, A.E., et al., J. Invest. Dermatol. 124(1):46-55 (2005). Suzuki, A., et al., Oncogene 23(42):7067-7075 (2004). Horowitz, P.M., et al., J. Neurosci. 24(36):7895-7902 (2004). Schmeck, B., et al., Infect. Immun. 72(9):4940-4947 (2004). Mendez, E., et al., J. Virol. 78(16):8601-8608 (2004).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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