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Antigenic Specificity | FLNA (Y1046), 1025-1054 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.48 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This FLNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1054 amino acids from human FLNA. Actin-binding protein 280, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers. |
Immunogen | n/a |
Other Names | [Filamin-A; FLN-A; Actin-binding protein 280; ABP-280; Alpha-filamin; Endothelial actin-binding protein; Filamin-1; Non-muscle filamin; FLNA; FLN; FLN1] |
Gene, Accession # | [FLNA], Gene ID: 2316, NCBI: NP_001104026.1, UniProt: P21333 |
Catalog # | MBS9202775 |
Price | $165, $370 |
Order / More Info | FLNA (Y1046), 1025-1054 Antibody from MYBIOSOURCE INC. |
Product Specific References | Ravid,D., Exp. Cell Res. 314 (15), 2762-2773 (2008) Maceyka,M., Mol. Cell. Biol. 28 (18), 5687-5697 (2008) |