CREB3L1, OASIS Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CREB3L1, OASIS |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CREB3L1, OASIS antibody detects endogenous levels of CREB3L1, OASIS. Function: Transcription factor involved in unfolded protein response (UPR). Binds the DNA consensus sequence 5'-GTGXGCXGC-3' (PubMed:21767813). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in bone formation through the trans |
| Immunogen | Immunogen: A synthesized peptide derived from human CREB3L1, OASIS. Subcellular Location: Endoplasmic Reticulum Membrane and Nucleus. Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus. Tissue Specificity: Expressed in several tissues, with highest levels in pancreas and prostate. Expressed at relatively lower levels in brain. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100 |
| Other Names | [BBF-2 homolog; CAMP responsive element binding protein 3 like 1; cAMP-responsive element-binding protein 3-like protein 1; CR3L1_HUMAN; Creb3l1; Cyclic AMP responsive element binding protein 3 like protein 1; OASIS; Old astrocyte specifically-induced substance; Processed cyclic AMP-responsive element-binding protein 3-like protein 1] |
| Gene, Accession # | [CREB3L1], Gene ID: 90993, NCBI: NP_443086.1, UniProt: Q96BA8 |
| Catalog # | MBS9603489 |
| Price | $240, $280 |
| Order / More Info | CREB3L1, OASIS Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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