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Antigenic Specificity | IL10RB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IL10RB antibody detects endogenous levels of total IL10RB. Function: Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.Subunit Structure: Heterodimer with IFNLR1.Similarity: Belongs to the type II cytokine receptor family. |
Immunogen | Immunogen: A synthesized peptide derived from human IL10RB Subcellular Location: Membrane. Predicted Cross Reactivity: Horse Similarity: Horse (80%) |
Other Names | [Cd210; CDw210b; CRF2 4; CRF2-4; CRFB4; Cytokine receptor class II; Cytokine receptor class II CRF2 4; Cytokine receptor class-II member 4; Cytokine receptor family 2 member 4; Cytokine receptor family II member 4; D21S58; D21S66; I10R2_HUMAN; IL-10 receptor subunit beta; IL-10R subunit 2; IL-10R subunit beta; IL-10R2; IL-10RB; IL10R2; IL10RB; Interleukin 10 receptor beta; Interleukin-10 receptor subunit 2; Interleukin-10 receptor subunit beta] |
Gene, Accession # | [IL10RB], Gene ID: 3588, NCBI: NP_000619.3, UniProt: Q08334 |
Catalog # | MBS9609274 |
Price | $240, $280 |
Order / More Info | IL10RB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |