TRPV4 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTRPV4 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, human, mouse, porcine, rabbit, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Western Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against TRPV4. It was validated on Western Blot using a cell lysate as a positive control.Target Description: TRPV4 is a non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation of TRPV4 by exposure to hypotonicity within the physiological range exhibits an outward rectification. TRPV4 also activated by low pH, citrate and phorbol esters and increase of intracellular Ca2+ potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism.Defects in TRPV4 are the cause of brachyolmia type 3 (BRAC3) This gene encodes a member of the OSM9-like transient receptor potential
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRPV4
Other Names[transient receptor potential cation channel subfamily V member 4 isoform b; Transient receptor potential cation channel subfamily V member 4; transient receptor potential cation channel subfamily V member 4; transient receptor potential cation channel subfamily V member 4; Osm-9-like TRP channel 4; OTRPC4; Transient receptor potential protein 12; TRP12; Vanilloid receptor-like channel 2; Vanilloid receptor-like protein 2; VRL-2; Vanilloid receptor-related osmotically-activated channel; VR-OAC]
Gene, Accession #[TRPV4], Gene ID: 59341, NCBI: NP_671737, UniProt: Q9HBA0
Catalog #MBS3202530
Price$365
Order / More InfoTRPV4 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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