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Antigenic Specificity | TRPV4 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, human, mouse, porcine, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against TRPV4. It was validated on Western Blot using a cell lysate as a positive control.Target Description: TRPV4 is a non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation of TRPV4 by exposure to hypotonicity within the physiological range exhibits an outward rectification. TRPV4 also activated by low pH, citrate and phorbol esters and increase of intracellular Ca2+ potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism.Defects in TRPV4 are the cause of brachyolmia type 3 (BRAC3) This gene encodes a member of the OSM9-like transient receptor potential |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRPV4 |
Other Names | [transient receptor potential cation channel subfamily V member 4 isoform b; Transient receptor potential cation channel subfamily V member 4; transient receptor potential cation channel subfamily V member 4; transient receptor potential cation channel subfamily V member 4; Osm-9-like TRP channel 4; OTRPC4; Transient receptor potential protein 12; TRP12; Vanilloid receptor-like channel 2; Vanilloid receptor-like protein 2; VRL-2; Vanilloid receptor-related osmotically-activated channel; VR-OAC] |
Gene, Accession # | [TRPV4], Gene ID: 59341, NCBI: NP_671737, UniProt: Q9HBA0 |
Catalog # | MBS3202530 |
Price | $365 |
Order / More Info | TRPV4 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |