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Antigenic Specificity | DNM1L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis; this requirement may depend upon the cell type and the phy |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 411-710 of human DNM1L (NP 036193.2). |
Other Names | [DLP1; DRP1; DVLP; EMPF; OPA5; EMPF1; DYMPLE; HDYNIV] |
Gene, Accession # | [DNM1L], Gene ID: 10059, NCBI: NP_005681.2, UniProt: O00429 |
Catalog # | MBS8545013 |
Price | $280 |
Order / More Info | DNM1L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |