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Antigenic Specificity | IL17RC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total IL17RC protein. This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracell |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human IL17RC. |
Other Names | [Interleukin-17 receptor C; IL-17 receptor C; IL-17RC; Interleukin-17 receptor-like protein; IL-17RL] |
Gene, Accession # | [IL17RC], Gene ID: 84818, NCBI: NP_001190192.1, UniProt: Q8NAC3 |
Catalog # | MBS9408158 |
Price | $200, $255 |
Order / More Info | IL17RC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |