Human FADD Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman FADD
Clonepolyclonal
Host SpeciesMouse
Reactive Speciesn/a
Isotypen/a
Formatperoxidase (HRP) conjugate
Size1 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunoblot (IB), Immunoprecipitation (IP)
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DescriptionSpecificity: Human FADD. Fas-associated death domain (FADD, also known as MORT1) is an important apoptosis adapter molecule involved in the Fas-mediated cell death pathway. FADD associates with the intracellular domain of FAS (CD95/APO-1) through their respective C-terminal death domains (DD). The N-terminal region of FADD contains a death effectors domain (DED) which recruits and binds cytosolic proteins such as FLICE/caspase-8. The subsequent activation of FLICE by proteolytic cleavage leads to the activation of the caspase-mediated (ICE-related proteases) apoptotic cascade. Overexpression of FADD induces apoptosis which is inhibited by CrmA, a specific inhibitor of the interleukin-1beta-converting enzyme. FADD has also been shown under c
ImmunogenImmunogen: Recombinant FADD. Buffer Formulation: Supplied in a stock solution in 50% glycerol/50% PBS, pH 7.4; No preservative added
Other Names[FAS-associated death domain protein; GIG3; MGC8528; MORT1], [FADD; FADD; GIG3; MORT1; MORT1]
Gene, Accession #[FADD], Gene ID: 8772, NCBI: CAG33019.1, UniProt: Q13158
Catalog #MBS670616
Price$375
Order / More InfoHuman FADD Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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