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Antigenic Specificity | PCID2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic |
Immunogen | Immunogen: Recombinant Human PCI domain-containing protein 2 protein (2-250AA) Conjugation: Non-conjugated |
Other Names | [PCI domain-containing protein 2; CSN12-like protein; PCID2; HT004] |
Gene, Accession # | [PCID2], Gene ID: 55795, NCBI: NP_001120674.1, UniProt: Q5JVF3 |
Catalog # | MBS7052897 |
Price | $160, $235 |
Order / More Info | PCID2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |