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Antigenic Specificity | CK-17 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to near N-terminal residues of CK17. Cytokeratin 17 may play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type |
Immunogen | n/a |
Other Names | [keratin, type I cytoskeletal 17; Keratin, type I cytoskeletal 17; keratin, type I cytoskeletal 17; keratin 17; Cytokeratin-17; CK-17; Keratin-17; K17], [Krt17; Krt17; K17; Krt1-17; Krt1-17; CK-17; K17] |
Gene, Accession # | [CK-17], Gene ID: 16667, NCBI: NP_034793.1, UniProt: Q9QWL7 |
Catalog # | MBS850196 |
Price | $280 |
Order / More Info | CK-17 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Fan W., Yoon K. Exp. Dermatol. 12:832-842(2003). 2. Tong X., Coulombe P.A. Genes Dev. 20:1353-1364(2006). 3. Kim S., Wong P., Coulombe P.A. Nature 441:362-365(2006). |