WAVE (Tyr-125), phospho-specific Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | WAVE (Tyr-125), phospho-specific |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody was cross-adsorbed to phospho-WAVE (Tyr-150) and unphosphorylated WAVE (Tyr-125) peptides before affinity purification using phospho-WAVE (Tyr-125) peptide. In western blots, the antibody detects an 80 kDa* band corresponding to phosphorylated WAVE in human SYF cSrc transformed cells and mouse macrophages treated with pervanadate, but is not observed in control cells. These bands can be specifically blocked with phospho-WAVE (Tyr-125) peptide (WX1775), but not phospho-WAVE (Tyr-150) peptide (WX1825). The Wiskott-Aldrich syndrome protein (WASP) family is involved in various pathways that regulate actin cytoskeletal organization. This family includes WASP, N-WASP, and three WAVE/SCAR isoforms, WAVEs 1, 2, and 3. WAVE proteins pl |
| Immunogen | Immunogen: Phospho-WAVE (Tyr-125) peptide (coupled to KLH) corresponding to amino acid residues surrounding Tyr-125 in human WAVE1. This sequence has high homology with similar regions in rat and mouse WAVE1, and has less than 50% homology to similar regions in the conserved site in WAVE2 (Tyr-124) and WAVE3 (Tyr-125). |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS472067 |
| Price | $385 |
| Order / More Info | WAVE (Tyr-125), phospho-specific Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Ardern, H. et al. (2006) Cell Motil. Cytosk. 63:6• Leng, Y. et al. (2005) PNAS 102(4):1098• Suetsugu, S. et al. (1999) Bioch. Biophs. Res. Comm. 260:296• Miki, H. et al. (1999) J Biol. Chem. 274(39):27605 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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