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Antigenic Specificity | SH3GL3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SH3GL3 antibody detects endogenous levels of total SH3GL3. Function: Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).Subunit Structure: Interacts with ARC (By similarity). Interacts with DNM1, SGIP1 and SYNJ1. Interacts with the huntingtin exon 1 protein (HDEX1P) containing a glutamine repeat in the pathological range and promotes formation of insoluble polyglutamine-containing aggregates in vivo. Interacts with DYDC1. Interacts with FASLG. Interacts with ATX2. Interacts with BIN2.Similarity: An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved |
Immunogen | Immunogen: A synthesized peptide derived from human SH3GL3 Subcellular Location: Cytoplasm. Early endosome membrane. Associated with postsynaptic endosomes in hippocampal neurons. Associated with presynaptic endosomes in olfactory neurons. Tissue Specificity: Brain and testis. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (82%), Bovine (91%), Horse (91%), Sheep (91%), Rabbit (100%), Dog (91%) |
Other Names | [CNSA3; EEN 2B L3; EEN B2; EEN-B2; EEN2BL3; EENB2; Endophilin 3; Endophilin A3; Endophilin-3; Endophilin-A3; H.sapiens mRNA for protein containing SH3 domain, SH3GL3; HsT19371; SH3 domain containing GRB2 like protein 3; SH3 domain GRB2 like 3; SH3 domain protein 2C; SH3 domain-containing GRB2-like protein 3; SH3D2C; SH3G3_HUMAN; SH3GL3; SH3P13] |
Gene, Accession # | [SH3GL3], Gene ID: 6457, NCBI: NP_001288037.1, UniProt: Q99963 |
Catalog # | MBS9610223 |
Price | $240, $280 |
Order / More Info | SH3GL3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |