RNF6 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RNF6 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: RNF6 antibody detects endogenous levels of total RNF6. Function: E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.Subunit Structure: Interacts with LIMK1 (By similarity). Interacts with AR.Similarity: Belongs to the RNF12 family. |
| Immunogen | Immunogen: A synthesized peptide derived from human RNF6 Subcellular Location: Nucleus. Cytoplasm. Cell Projection > Axon. Nucleus > PML Body. Localizes to the PML nuclear bodies in Sertoli cells. Tissue Specificity: Weakly expressed in peripheral blood, spleen, prostate, testis and ovary. According to PubMed:18368307, it is preferentially expressed in testis and ovary and hardly detected in other tissues. Predicted Cross Reactivity: Horse Similarity: Horse (80% |
| Other Names | [E3 ubiquitin-protein ligase RNF6; Ring finger protein (C3H2C3 type) 6; Ring finger protein 6; RING H2 protein; RING H2 protein RNF6; RNF 6; RNF6; RNF6_HUMAN; SPG2] |
| Gene, Accession # | [RNF6], Gene ID: 6049, NCBI: NP_005968.1, UniProt: Q9Y252 |
| Catalog # | MBS9609207 |
| Price | $240, $280 |
| Order / More Info | RNF6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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