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Antigenic Specificity | CREB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity. Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1. CREB appears to play an important role in learning and memory in both flies and mice. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 109 of rat CREB |
Other Names | [CREB-1; cAMP-response Element-binding Protein-1; CREB1; CREB; MGC9284], [Creb1; Creb1; Creb; Creb-1; CREB-1; cAMP-responsive element-binding protein 1] |
Gene, Accession # | [CREB], Gene ID: 81646, NCBI: NP_112279.1, UniProt: P15337 |
Catalog # | MBS840162 |
Price | $150, $290 |
Order / More Info | CREB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |