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Antigenic Specificity | CHRNG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myast |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [acetylcholine receptor subunit gamma; Acetylcholine receptor subunit gamma; acetylcholine receptor subunit gamma; cholinergic receptor, nicotinic, gamma (muscle)] |
Gene, Accession # | [CHRNG], Gene ID: 1146, NCBI: NP_005190.4, UniProt: P07510 |
Catalog # | MBS9128183 |
Price | $200, $275, $430 |
Order / More Info | CHRNG Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |