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Antigenic Specificity | MAP2K7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | c-Jun NH2-terminal protein kinase (JNK), a distant member of the mitogen-activated protein (MAP) kinase family, regulates gene expression in response to various extracellular stimuli. MKK7, a novel member of the MAP kinase kinase family, was phosphorylated and activated by MEKK1, a MAP kinase kinasekinase in the JNK signaling cascade. MKK7 activity was also stimulated by constitutively active forms of Rac and Cdc42Hs, members of the Rho small GTP-binding protein family (1). endogenous MKK7 was activated by treatment with the growth factor interleukin-3 (but not interleukin-4), or by ligation of CD40, the B-cell antigen receptor, or the receptor for the Fc fragment of immunoglobulin. MKK7 was also activated when cells were exposed to heat, U |
Immunogen | Immunogen: Recombinant protein of human MAP2K7 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [MAP2K7; Jnkk2; MAPKK7; MKK7; PRKMK7; SAPKK-4; SAPKK4] |
Gene, Accession # | [MAP2K7], Gene ID: 5609, NCBI: NP_001284484.1, UniProt: O14733 |
Catalog # | MBS8505660 |
Price | $310 |
Order / More Info | MAP2K7 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Lu X, et al. J BiolChem 272(40):24751-4, 1997. 2. Foltz IN, et al. J BiolChem 273(15):9344-51, 1998. |