MAP2K7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMAP2K7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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Descriptionc-Jun NH2-terminal protein kinase (JNK), a distant member of the mitogen-activated protein (MAP) kinase family, regulates gene expression in response to various extracellular stimuli. MKK7, a novel member of the MAP kinase kinase family, was phosphorylated and activated by MEKK1, a MAP kinase kinasekinase in the JNK signaling cascade. MKK7 activity was also stimulated by constitutively active forms of Rac and Cdc42Hs, members of the Rho small GTP-binding protein family (1). endogenous MKK7 was activated by treatment with the growth factor interleukin-3 (but not interleukin-4), or by ligation of CD40, the B-cell antigen receptor, or the receptor for the Fc fragment of immunoglobulin. MKK7 was also activated when cells were exposed to heat, U
ImmunogenImmunogen: Recombinant protein of human MAP2K7 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[MAP2K7; Jnkk2; MAPKK7; MKK7; PRKMK7; SAPKK-4; SAPKK4]
Gene, Accession #[MAP2K7], Gene ID: 5609, NCBI: NP_001284484.1, UniProt: O14733
Catalog #MBS8505660
Price$310
Order / More InfoMAP2K7 Antibody from MYBIOSOURCE INC.
Product Specific References1. Lu X, et al. J BiolChem 272(40):24751-4, 1997. 2. Foltz IN, et al. J BiolChem 273(15):9344-51, 1998.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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