p38 alpha MAP Kinase (C-terminal) Antibody from MYBIOSOURCE INC.

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Antigenic Specificityp38 alpha MAP Kinase (C-terminal)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, rat, mouse
IsotypeIgG1
FormatProtein A purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA, Western Blot, Immunocytochemistry
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DescriptionThis antibody detects a 42 kDa* protein corresponding to the apparent molecular mass of p38-alpha on SDS-PAGE immunoblots of human Jurkat, A431, and HeLa cells. p38 MAP kinase (MAPK), also called RK, CSBP, and SAPK2a, is the mammalian orthologue of the yeast HOG kinase. This family of kinases participates in signaling cascades that control cellular responses to cytokines and stress. Four isoforms of p38 MAPK (alpha, beta, gamma, delta) have been identified. Similar to the SAPK/JNK pathway, p38 MAPK is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharides, UV light and growth factors. MKK3 and SEK activate p38 MAPK by dual phosphorylation at threonine 180 and tyrosine 182. Activated
ImmunogenImmunogen: Clone M138 was generated from a recombinant protein corresponding to amino acid residues in the C-terminal region of rat p38-alpha. This sequence is identical in human and mouse p38-alpha.
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS470021
Price$325
Order / More Infop38 alpha MAP Kinase (C-terminal) Antibody from MYBIOSOURCE INC.
Product Specific References• Han, J. et al. (1994) Science 265, 808-811.• Lee, J. C. et al. (1994) Nature 372, 739-746.• Rouse, J. et al. (1994) Cell 78, 1027-1037.• Freshney, N. W. et al. (1994) Cell 78, 1039-1049.• Raingeaud, J. et al. (1995) J. Biol. Chem. 270, 7420-7426.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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