EAAT1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | EAAT1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat. |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 1 (SLC1A3) detection. Background: Solute carrier family 1 (glial high-affinity glutamate transporter), member 3, also known as SLC1A3, EAAT1 or GLAST, is a protein that in humans is encoded by the SLC1A3 gene. This gene is a member of high affinity glutamate transporter family. It is mapped to chromosome 5p13.2 by fluorescence in situ hybridization (FISH). And this gene transports L-glutamate and also L- and D-aspartate. It is essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Furthermore, this gene acts as a symport by cotransporting sodium. |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human EAAT1 (14-42aa RMERFQQGVRKRTLLAKKKVQNITKEDVK), different from the related mouse sequence by three amino acids, and identical to the related rat sequence. |
| Other Names | [EA6; EAA1; EAAT 1; EAAT1; EAAT1; GLAST; GLAST1; Glast; GLAST-1; SLC1A3; P43003; Excitatory amino acid transporter 1; solute carrier family 1 (glial high affinity glutamate transporter), member 3], [SLC1A3; SLC1A3; EA6; EAAT1; GLAST; GLAST1; EAAT1; GLAST; GLAST1; GLAST-1] |
| Gene, Accession # | [SLC1A3], Gene ID: 6507, NCBI: NP_001160167.1, UniProt: P43003 |
| Catalog # | MBS178459 |
| Price | $315 |
| Order / More Info | EAAT1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. de Vries, B., Mamsa, H., Stam, A. H., Wan, J., Bakker, S. L. M., Vanmolkot, K. R. J., Haan, J., Terwindt, G. M., Boon, E. M. J., Howard, B. D., Frants, R. R., Baloh, R. W., Ferrari, M. D., Jen, J. C., van den Maagdenberg, A. M. J. M. Episodic ataxia associated with EAAT1 mutation C186S affecting glutamate reuptake. Arch. Neurol. 66: 97-101, 2009. Note: Errata: Arch. Neurol. 66: 497 only, 2009; Arch. Neurol. 66: 772 only, 2009.2. Matsugami, T. R., Tanemura, K., Mieda, M., Nakatomi, R., Yamada, K., Kondo, T., Ogawa, M., Obata, K., Watanabe, M., Hashikawa, T., Tanaka, K. Indispensability of the glutamate transporters GLAST and GLT1 to brain development. Proc. Nat. Acad. Sci. 103: 12161-12166, 2006. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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