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Antigenic Specificity | Nephrin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Nephrin Polyclonal Antibody detects endogenous levels of Nephrin protein. NPHS1 encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. NPHS1 is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes. |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human Nephrin |
Other Names | [Rabbit Nephrin; NPHS1; Nephrin; Renal glomerulus-specific cell adhesion receptor] |
Gene, Accession # | [NPHN], Gene ID: 4868, NCBI: AAG17141.1, UniProt: O60500 |
Catalog # | MBS9706044 |
Price | $130, $220, $325 |
Order / More Info | Nephrin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |