Edit |   |
Antigenic Specificity | GABRB3 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | mouse, rat. predicted to work with: human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Gamma-aminobutyric acid receptor subunit beta-3(GABRB3) detection. Tested with WB in Human;Mouse; Rat. Background: This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. And this gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. It may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively s |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human GABRB3 (344-375aa EKTAKAKNDRSKSESNRVDAHGNILLTSLEVH), different from the related mouse and rat sequences by five amino acids. Ig Type: Rabbit IgG |
Other Names | [Gamma-aminobutyric acid receptor subunit beta-3; ECA5; GABA A receptor beta 3 subunit; GABA A receptor subunit beta 3; GABA alpha receptor beta 3 subunit; GABA alpha receptor beta-2 subunit; GABA(A) receptor beta 3 subunit; GABA(A) receptor subunit beta 3; GABA(A) receptor subunit beta-3; GABAA receptor beta 3 subunit; GABAA receptor subunit beta 3; GABR B3; GABRB 3; GABRB3; Gamma aminobutyric acid (GABA) A receptor beta 3; Gamma aminobutyric acid A receptor beta 3; Gamma aminobutyric acid receptor subunit beta 3; Gamma-aminobutyric acid receptor subunit beta-3; GBRB3_HUMAN; MGC9051; gamma-aminobutyric acid (GABA) A receptor, beta 3], [GABRB3; GABRB3; ECA5] |
Gene, Accession # | [GABRB3], Gene ID: 2562, NCBI: NP_000805.1, UniProt: P28472 |
Catalog # | MBS178093 |
Price | $280 |
Order / More Info | GABRB3 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. DeLorey TM, Sahbaie P, Hashemi E, Homanics GE, Clark JD (March 2008).Gabrb3 gene deficient mice exhibit impaired social and exploratory behaviors, deficits in non-selective attention and hypoplasia of cerebellar vermal lobules: a potential model of autism spectrum disorder. Behav. Brain Res. 187 (2): 207-20. 2. Entrez Gene: GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3. |