Edit |   |
---|---|
Antigenic Specificity | CXCR4 (EL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-CXCR4 (EL) [Rabbit antibody to peptide corresponding to aa 182-196 in the second extracellular loop of human CXCR4.]. This antibody recognizes human and mouse CXCR4 (40 kD). Human immunodeficiency virus (HIV) and related viruses require coreceptors in addition to CD4 to infect target cells. Some G proteincoupled receptors in the chemokine receptor family, including CCR5, CXCR4, CCR3, CCR2b, and CCR8 in the chemokine receptor family, have been identified as HIV coreceptors. CXCR4 (also called Fusin, LESTR, HUMSTR) is a principal coreceptor for T-cell tropic strains of HIV-1. CXCR4 is also required for the infection by dual-tropic strains of HIV-1 and mediates CD4-independent infection by HIV-2. The alpha-chemokine SDF-1 is |
Immunogen | Antigen: Peptide corresponding to aa 182- 196 in the second extracellular loop (EL) of human CXCR4. |
Other Names | [CXCR4 (EL); HIV Co-Receptor CXCR4 (EL)], [CXCR4; CXCR4; FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LESTR; NPY3R; NPYRL; HSY3RR; NPYY3R; D2S201E] |
Gene, Accession # | Gene ID: 7852, NCBI: CAA12166.1, UniProt: P61073 |
Catalog # | MBS194054 |
Price | $415 |
Order / More Info | CXCR4 (EL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |