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Antigenic Specificity | IL27 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Interleukin 27 (IL-27) is a member of the IL-12 cytokine family. The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).Protein Function: Associates with EBI3 to form the IL-27 interleukin, a het |
Immunogen | Immunogen: E Coli-derived mouse IL27 recombinant protein (Position: F29-S234). Subcellular Localization: Secreted. Tissue Specificity: Expressed in macrophages and dendritic cells. |
Other Names | [Interleukin-27 subunit alpha; IL-27 subunit alpha; IL-27-A; IL27-A; p28; Il27; Il27a] |
Gene, Accession # | [IL27], Gene ID: 246779, NCBI: NP_663611.1, UniProt: Q8K3I6 |
Catalog # | MBS1750495 |
Price | $280 |
Order / More Info | IL27 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |