ATRX Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityATRX
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunofluorescence (IF)
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DescriptionThe antibody detects endogenous levels of total ATRX protein. Involved in transcriptional regulation and chromatin remodeling. Facilitates DNA replication in multiple cellular environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into regular chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes. Catalytic component of the chromatin remodeling complex ATRX:DAXX which has ATP-dependent DNA translocase activity and catalyzes the replication-independent deposition of histone H3.3 in pericentric DNA repeats outside S-phase and telo
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from N-terminal of human ATRX.
Other Names[EC 3.6.1.-; RAD54L; Transcriptional regulator ATRX; X-linked helicase II; X-linked nuclear protein]
Gene, Accession #[ATRX], Gene ID: 546, NCBI: NP_000480.3, UniProt: P46100
Catalog #MBS9410230
Price$200, $255
Order / More InfoATRX Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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