GALE Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGALE
Clone[AT6G10]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, k
FormatProtein A purified
Size0.05 mL, 0.1 mL
Concentration1 mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionThe enzyme UDP-glucose 4-epimerase, also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This enzyme performs the final step in the Leloir pathway of galactose metabolism, catalyzing the reversible conversion of UDP-galactose to UDP-glucose. GALE tightly binds nicotinamide adenine dinucleotide (NAD+), a co-factor required for catalytic activity. Additionally, human and some bacterial GALE isoforms reversibly catalyze the formation of UDP-N-acetylgalactosamine (UDP-GalNAc) from UDP-N-acetylglucosamine (UDP-GlcNAc) in the presence of NAD+, an initial step in glycoprotein or glycolipid synthesis.
ImmunogenImmunogen: Recombinant human GALE (1-348aa) purified from E. coli
Other Names[uDP-glucose 4-epimeraes; SDR1E1.uDP-glucose 4-epimeraes; uDP-galactose 4-epimerase; Galactowaldenase; FLJ95174; FLJ97302], [GALE; GALE; SDR1E1; UDP-GlcNAc 4-epimerase]
Gene, Accession #[GALE], Gene ID: 2582, NCBI: NP_000394, UniProt: Q14376
Catalog #MBS200403
Price$240, $315
Order / More InfoGALE Antibody from MYBIOSOURCE INC.
Product Specific ReferencesHolden HM., et al. (2003) J. Biol. Chem. 278 (45): 43885-8.; Liu Y., et al. (1996) Biochemistry. 35 (23): 7615-20.; Thoden Jb., et al. (2001) J. Biol. Chem. 276 (18): 15131-6.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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