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Antigenic Specificity | CCR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, monkey |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Chemokines play an important role in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein, eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation. |
Immunogen | Immunogen: CCR1 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 341 of human CCR1 as the immunogen. |
Other Names | [Rabbit CCR1; CCR1; CCR1; C-C chemokine receptor type 1; MIP1aR; CD191; CCR1; CCR-1; CMKBR1; CKR-1; HM145; CCR 1; CMKR1; CCR 1; CCR-1] |
Gene, Accession # | [CCR1], Gene ID: 1230, UniProt: P32246 |
Catalog # | MBS5311298 |
Price | $490 |
Order / More Info | CCR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |