Edit |   |
---|---|
Antigenic Specificity | ERLIN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex (PubMed:24217618). |
Immunogen | Immunogen: Recombinant human Erlin-1 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-244210 / sc-244211 |
Other Names | [Erlin-1; ERLIN1; C10orf69; KE04; KEO4; SPFH1; Endoplasmic reticulum lipid raft-associated protein 1; Protein KE04; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1; SPFH domain-containing protein 1], [ERLIN1; ERLIN1; KE04; KEO4; SPFH1; SPG62; Erlin-1; C10orf69; C10orf69; KE04; KEO4; SPFH1; SPFH domain-containing protein 1] |
Gene, Accession # | [ERLIN1], Gene ID: 10613, NCBI: NP_001094096.1, UniProt: O75477 |
Catalog # | MBS1494839 |
Price | $160, $235 |
Order / More Info | ERLIN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |