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Antigenic Specificity | CD79a (B-Cell Marker) |
Clone | [IGA/1688R] |
Host Species | Rabbit |
Reactive Species | human, mouse, rat. |
Isotype | IgG |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). T |
Immunogen | Immunogen: A synthetic peptide corresponding to aa 202-216 (GTYQDVGSLNIADVQ) of human CD79a protein. Cellular Localization: Cell Surface |
Other Names | [B lymphocyte-specific MB1 protein; B-cell antigen receptor complex-associated protein alpha chain; CD79a molecule immunoglobulin associated alpha; Ig-alpha; IGA; IgM-alpha; Immunoglobulin-associated alpha; Ly54; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein] |
Gene, Accession # | [CD79a], Gene ID: 973, NCBI: NP_001774.1, UniProt: P11912 |
Catalog # | MBS4380369 |
Price | $190, $340, $340 |
Order / More Info | CD79a (B-Cell Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Mason, DY, et al. 1995. Blood 86: 1453-1459. |