Human CD261 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD261
Clone[DR-4-02]
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1
Formatunconjugated
Size0.025 mg
ConcentrationIgG concentration 1.0 mg/ml
ApplicationsFlow cytometry (FC/FACS), Immunoprecipitation (IP)
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DescriptionMouse anti Human CD261 antibody, clone DR-4-02 recognizes human death receptor 4 (DR4), also known as CD261 or TRAIL- R1. DR4 is a type I transmembrane protein of 468 amino acids, which is expressed in most human tissues including spleen, peripheral blood leucocytes, thymus and in a variety of tumour-derived cell lines. DR4 plays a role in inducing cell death. The binding of TRAIL to DR4 triggers the activation of pro-caspases 8 and 10, leading to apoptosis.
ImmunogenImmunogen: Fusion protein containing the extracellular region of CD261 (DR4). Fusion Partners: Spleen cells from immunised F1 hybrid mice were fused with cells of the SP2/0-Ag14 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human
Other Names[tumor necrosis factor receptor superfamily member 10A; Tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10A; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; cytotoxic TRAIL receptor; death receptor 4; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; CD_antigen: CD261], [TNFRSF10A; TNFRSF10A; DR4; APO2; CD261; TRAILR1; TRAILR-1; APO2; DR4; TRAILR1; TRAIL receptor 1; TRAIL-R1]
Gene, Accession #[CD261], Gene ID: 8797, NCBI: NP_003835.3, UniProt: O00220
Catalog #MBS215943
Price$175
Order / More InfoHuman CD261 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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