Edit |   |
Antigenic Specificity | Phospho-PKN2 (Ser815) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-PKN2 (Ser815) Antibody detects endogenous levels of PKN2 only when phosphorylated at Ser815. Description: PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes. Phosphorylates CTTN in hyaluronan-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin. Phosphorylates HDAC5, therefore lead to impair HDAC5 import. Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junc |
Immunogen | Immunogen: A synthesized peptide derived from human PKN2 around the phosphorylation site of Ser815. Tissue Specificity: Ubiquitous. Expressed in numerous tumor cell lines, especially in bladder tumor cells. |
Other Names | [Cardiolipin activated protein kinase Pak2; MGC150606; MGC71074; PAK 2; PAK2; PKN gamma; PKN2; PKN2_HUMAN; PRK2; PRKCL2; PRO2042; Protein kinase C like 2; Protein kinase C related kinase 2; Protein kinase C-like 2; Protein kinase N2; Protein-kinase C-related kinase 2; Serine/threonine-protein kinase N2] |
Gene, Accession # | [PKN2], Gene ID: 5586, NCBI: Q16513.1, UniProt: Q16513 |
Catalog # | MBS9610768 |
Price | $225, $280, $340 |
Order / More Info | Phospho-PKN2 (Ser815) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |