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Antigenic Specificity | Phospho-FAK (Tyr576) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-FAK (Tyr576) antibody detects endogenous levels of FAK only when phosphorylated at Tyrosine 576. Description: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents.Function: Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migr |
Immunogen | Immunogen: A synthesized peptide derived from human FAK around the phosphorylation site of Tyrosine 576 Subcellular Location: Cell Junction > Focal Adhesion. Cell Membrane. Constituent of focal adhesions. Tissue Specificity: Detected in B and T-lymphocytes. Isoform 1 and isoform 6 are detected in lung fibroblasts (at protein level). Ubiquitous. Predicted Cross Reactivity: Pig, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Horse (100%), Shee |
Other Names | [FADK 1; FADK; FAK related non kinase polypeptide; FAK1; FAK1_HUMAN; Focal adhesion kinase 1; Focal adhesion Kinase; Focal adhesion kinase isoform FAK Del33; Focal adhesion kinase related nonkinase; FRNK; p125FAK; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; Protein tyrosine kinase 2; Protein-tyrosine kinase 2; Ptk2; PTK2 protein tyrosine kinase 2] |
Gene, Accession # | [FAK], Gene ID: 5747, NCBI: NP_001186578.1, UniProt: Q05397 |
Catalog # | MBS9601166 |
Price | $240, $280 |
Order / More Info | Phospho-FAK (Tyr576) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |