CD45/LCA (Leucocyte Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD45/LCA (Leucocyte Marker) |
| Clone | [2B11 + PD7/26] |
| Host Species | Mouse |
| Reactive Species | human, dog |
| Isotype | IgG1, kappa + IgG1, kappa |
| Format | fluorescein (FITC) conjugate |
| Size | 0.5 mL |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes the CD45 leukocyte common antigen (LCA) family which is comprised of at least four isoforms of membrane glycoproteins (220, 205, 190, 180kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellular portions of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms. A positive result with this MAb is highly indicative of lymphoid or myeloid origin. Certain types of lymphoid neoplasms may lack CD45 (Hodgkin lymphoma, some T-cell lymphomas, and some leukemias) so its abse |
| Immunogen | Immunogen: Isolated neoplastic cells from T cell lymphoma (2B11); and human peripheral blood lymphocytes maintained in T cell growth factor (PD7/26) |
| Other Names | [B220; CD45R; GP180; Leukocyte common antigen (LCA); Loc; Ly-5; Lyt-4; Protein tyrosine phosphatase receptor type C (PTPRC); Receptor-type tyrosine-protein phosphatase C; T200 glycoprotein] |
| Gene, Accession # | [CD45/LCA], Gene ID: 5788, NCBI: NP_002829.3, UniProt: P08575 |
| Catalog # | MBS4381216 |
| Price | $340 |
| Order / More Info | CD45/LCA (Leucocyte Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Michie SA et. al. American Journal of Clinical Pathology, 1987, 88(4):457-62. 2. Gatter KC et. al. Lancet, 1985 Jun 8, 1(8441):1302-5. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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