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Antigenic Specificity | IRAK Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Interleukin-1 receptor-associated kinase 1, also called IRAK1, is an enzyme that in humans is encoded by the IRAK1 gene. By radiation hybrid analysis, this gene is mapped to chromosome Xq28. Serine/threonine-protein kinase plays a critical role in initiating innate immune response against foreign pathogens. This gene involved in Toll-like receptor (TLR) and IL-1R signaling pathways. This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.Protein Function: Serine/threonine-protein kinase tha |
Immunogen | Immunogen: E Coli-derived human IRAK recombinant protein (Position: M377-D479). Subcellular Localization: Cytoplasm. Tissue Specificity: Isoform 1 and isoform 2 are ubiquitously expressed in all tissues examined, with isoform 1 being more strongly expressed than isoform 2. |
Other Names | [Interleukin-1 receptor-associated kinase 1; IRAK-1; IRAK1; IRAK] |
Gene, Accession # | [IRAK], Gene ID: 3654, NCBI: NP_001020413.1, UniProt: P51617 |
Catalog # | MBS1750547 |
Price | $280 |
Order / More Info | IRAK Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |