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Antigenic Specificity | Keratocan |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Keratocan(KERA) detection. Tested with WB in Human;Mouse. Background: Keratocan (KTN), also known as keratan sulfate proteoglycan keratocan, is a protein that in humans is encoded by the KERA gene. It is mapped to 12q22. The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2). Keratan sulfate proteoglycans (KSPGs) are members of the small leucine-rich proteoglycan (SLRP) family. KSPGs, particularly keratocan, lumican and mimecan, are important to the transparency of the cornea. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Keratocan (77-109aa YLQNNLIETIPEKPFENATQLRWINLNKNKITN), different from the related mouse sequence by two amino acids. Ig Type: Rabbit IgG |
Other Names | [Keratocan; CNA2; KERA; KERA_HUMAN; Keratan sulfate proteoglycan keratocan; Keratocan; KTN; SLRR2B; keratocan], [KERA; KERA; KTN; CNA2; SLRR2B; SLRR2B; KTN] |
Gene, Accession # | Gene ID: 11081, NCBI: NP_008966.1, UniProt: O60938 |
Catalog # | MBS177729 |
Price | $280 |
Order / More Info | Keratocan Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: KERA keratocan. 2. Pellegata NS, Dieguez-Lucena JL, Joensuu T, Lau S, Montgomery KT, Krahe R, Kivela T, Kucherlapati R, Forsius H, de la Chapelle A (Jun 2000). Mutations in KERA, encoding keratocan, cause cornea plana. Nat Genet 25(1): 91-5. 3. Tasheva ES, Funderburgh JL, Funderburgh ML, Corpuz LM, Conrad GW (Jan 2000). Structure and sequence of the gene encoding human keratocan. DNA Seq 10 (1): 67-74. |