Acetylated Lysine Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAcetylated Lysine
Clonepolyclonal
Host SpeciesRabbit
Reactive SpeciesMulti species
Isotypen/a
Formatperoxidase (HRP) conjugate
Size0.4 mL
Concentration0.25mg/mL
ApplicationsWestern Blot (WB), ELISA (EIA), Immunoprecipitation (IP), Immunofluorescence (IF)
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DescriptionBackground Info: Detects proteins containing acetylated lysine residues in SDS PAGE immunoblots. Scientific Background: Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common post-transcriptional modification of Lysine involves acetylation (1). The conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) (2). Protein posttranslational reversible lysine Nepsilon-acetylation and deacetylation have been recognized as an emerging intracellular
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS805559
Price$460
Order / More InfoAcetylated Lysine Antibody from MYBIOSOURCE INC.
Product Specific References1. Yang XJ. (2005). Oncogene. 24:1653-1662. 2. Hassig, C.A. and Schreiber, S.L. (1997). Curr. Opin. Chem. Biol. 1(3): 300-308. 3. Yang XJ. (2004). Bioessays 26:1076-1087. 4. Hughes, R.E. (2002). Curr. Biol. 12: R141-R143. 5. Vigushin, D.M. and Coombes, R.C. (2004). Curr. Cancer Drug Targets 4: 205-218. 6. Chan, H.M. et al. (2001). Nat. Cell Biol. 3: 667-. 674. 7. Martinez-Balbas, M.A. et al. (2000). EMBO J. 19: 662-671.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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