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Antigenic Specificity | beta-synuclein (108-125) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Less than 0.1% cross reactivity to human alpha synuclein. Beta-synuclein is a non-amyloid component of senile plaques found in Alzheimer disease. It could act as a regulator of SNCA aggregation. It protects nerurons from staurosporine and 6 hydroxy dopamine-stimulated capspase activation in a p53-dependent manner. It localises to the cytoplasm and it is predominantly expressed in the brain where it is most concentrated in presynaptic nerve terminals. This protein is phosphorylated. This protein is also associated with the disease Brain iron accumulation type 1 (NBIA1). |
Immunogen | Immunogen: A synthetic peptide (IEPLMEPEGSYEDPPQE) of human beta synuclein protein (aa: 108-125) conjugated to diphteria toxid has been used as the immunogen. Storage Buffer: PBS, pH 7.4 with 0.02% sodium azide. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS4152681 |
Price | $515 |
Order / More Info | beta-synuclein (108-125) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |